Channel: Deregulated nutrient sensing

Deregulated impact on a cell's ability to recognize, and respond to, changes in the concentration of macronutrients such as glucose, fatty acids, and amino acids. Wikipedia (CC BY-SA 3.0)

2023 Articles

47 550 articles

Hunger potentiated

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Timing of food intake affects energy expenditure

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Endogenous DAF-16 spatiotemporal activity quantitatively predicts lifespan extension induced by dietary restriction

  • Javier Huayta, Joseph P Crapster, Javier Huayta, …, Javier Huayta, Joseph P Crapster, Adriana San-Miguel
  • Commun Biol, 10.1038/s42003-023-04562-2
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Lysine metabolism at the nexus of crotonylation and tumor immunity

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Melanocortin-4 receptors on neurons in the parabrachial nucleus mediate inflammation-induced suppression of food-seeking behavior

  • Kiseko Shionoya, Anna Nilsson, Linda Engström Ruud, …, Linda Engström Ruud, David Engblom, Anders Blomqvist
  • Brain Behav Immun, 10.1016/j.bbi.2023.02.014
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Hypothalamic Grb10 enhances leptin signalling and promotes weight loss

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Timed feeding aligns the adipocyte clock to optimize thermogenesis when eating a high-fat diet

  • Paramita Pati, Jennifer S Pollock, Karen L Gamble, …, Paramita Pati, Jennifer S Pollock, Karen L Gamble
  • Cell Metab, 10.1016/j.cmet.2022.12.008
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Nuclear remodeling drives age-related cardiac dysfunction

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Electrophysiological Comparison of Definitive Pro-opiomelanocortin Neurons in the Arcuate Nucleus and the Retrochiasmatic Area of Male and Female Mice

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2022 Articles

5 615 articles

Energy intake at the intersection of the clock and ageing

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The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster

  • Allyson S Munneke, Tuhin S Chakraborty, Saige S Porter, …, Saige S Porter, Christi M Gendron, Scott D Pletcher
  • None, 10.3389/fragi.2022.1068455
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Diurnal variations of triglyceride accumulation in mouse and bovine adipocyte-derived cell lines

  • Rena Shiraishi, Satomi Morita, Yoshikuni Goto, …, Yasushi Mizoguchi, Wataru Nakamura, Takahiro J Nakamura
  • Anim Sci J, 10.1111/asj.13802
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Hedgehog-mediated gut-taste neuron axis controls sweet perception in Drosophila

  • Yunpo Zhao, Mohammed A Khallaf, Emilia Johansson, …, Bill S Hansson, Markus Knaden, Mattias Alenius
  • Nat Commun, 10.1038/s41467-022-35527-4
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Circadian Control of Gastrointestinal Motility

  • Anita J L Leembruggen, Lincon A Stamp, Joel C Bornstein, …, Lincon A Stamp, Joel C Bornstein, Marlene M Hao
  • Adv Exp Med Biol, 10.1007/978-3-031-05843-1_18
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The Effect of Diet on the Cardiac Circadian Clock in Mice: A Systematic Review

  • Ana Beatriz Rezende Paula, Letícia Teresinha Resende, Isabela Alcântara Barretto Araújo Jardim, …, Maria Cecília Teles, Ana Maria de Lauro Castrucci, Mauro César Isoldi
  • None, 10.3390/metabo12121273
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Circadian signatures of anterior hypothalamus in time-restricted feeding

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UCP2-dependent redox sensing in POMC neurons regulates feeding

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Genetic basis of enhanced stress resistance in long-lived mutants highlights key role of innate immunity in determining longevity

  • Sonja K Soo, Annika Traa, Zenith D Rudich, …, Alibek Moldakozhayev, Meeta Mistry, Jeremy M Van Raamsdonk
  • Aging Cell, 10.1111/acel.13740
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Leptin and energy balance: exploring Leptin’s role in the regulation of energy intake and energy expenditure

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