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2023 Articles
8 448 articles
Metabolic individuality: Limitations, challenges, and potential for clinical utility
- Sarah H Elsea, Jennifer E Posey, Sarah H Elsea, Jennifer E Posey, Sarah H Elsea, Jennifer E Posey
- Cell Metab, 10.1016/j.cmet.2023.01.007
Genetic evidence implicating natriuretic peptide receptor-3 in cardiovascular disease risk: a Mendelian randomization study
- Héléne T Cronjé, Ville Karhunen, G Kees Hovingh, …, Jens O Lagerstedt, Michael Nyberg, Dipender Gill
- BMC Med, 10.1186/s12916-023-02867-x
Characterizing the polygenic architecture of complex traits in populations of East Asian and European descent
- Antonella De Lillo, Frank R Wendt, Gita A Pathak, …, Frank R Wendt, Gita A Pathak, Renato Polimanti
- Hum Genomics, 10.1186/s40246-023-00514-3
Empowering Beginners in Bioinformatics with ChatGPT
- Evelyn Shue, Li Liu, Bingxin Li, …, Zifeng Feng, Xin Li, Gangqing Hu
- bioRxiv : the preprint server for biology, 10.1101/2023.03.07.531414
Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
- Danielle Posthuma, Wouter J Peyrot, Danielle Posthuma, …, Emil Uffelmann, Danielle Posthuma, Wouter J Peyrot
- Sci Rep, 10.1038/s41598-023-29428-9
Genotyping and population characteristics of the China Kadoorie Biobank
- Robin G Walters, Iona Y Millwood, Kuang Lin, …, Robert J Clarke, Liming Li, Zhengming Chen
- None, 10.1016/j.xgen.2023.100361
Seeing humans through an evolutionary lens
- Irene Gallego Romero, Irene Gallego Romero, Irene Gallego Romero, Irene Gallego Romero, Irene Gallego Romero
- Science, 10.1126/science.adh0745
Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH
- Josephine H Li, Laura N Brenner, Varinderpal Kaur, …, Aaron Leong, Josep M Mercader, Jose C Florez
- Diabetologia, 10.1007/s00125-023-05922-7
DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural Network
- Yun Li, Jia Wen, Gang Li, …, Jin Szatkiewicz, Xin He, Patrick Sullivan
- Research square, 10.21203/rs.3.rs-2399024/v1
Toward FAIR Knowledge Turns in Bioinformatics
- Robert Schuler, Alejandro Bugacov, Matthew Blow, …, Alejandro Bugacov, Matthew Blow, Carl Kesselman
- None, 10.1109/bibm47256.2019.8982988
2022 Articles
857 articles
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies
- Xihao Li, Corbin Quick, Hufeng Zhou, …, Gina M Peloso, Zilin Li, Xihong Lin
- Nat Genet, 10.1038/s41588-022-01225-6
A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets
- Sanghun Lee, Georg Hahn, Julian Hecker, …, Rudolph E Tanzi, Christoph Lange, Dmitry Prokopenko
- Brief Bioinform, 10.1093/bib/bbac611
Genetic influences on human blood metabolites in the Japanese population
- Takeshi Iwasaki, Yoichiro Kamatani, Kazuhiro Sonomura, …, Koichiro Ohmura, Taka-Aki Sato, Fumihiko Matsuda
- None, 10.1016/j.isci.2022.105738
Comprehensive 100-bp resolution genome-wide epigenomic profiling data for the hg38 human reference genome
- Ronnie Y Li, Yanting Huang, Zhiyue Zhao, …, Yanting Huang, Zhiyue Zhao, Zhaohui S Qin
- None, 10.1016/j.dib.2022.108827
Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer’s disease through polygenic risk and RNA sequencing
- Karen Crawford, Ganna Leonenko, Emily Baker, …, Michael C O’Donovan, Valentina Escott-Price, Dobril K Ivanov
- Mol Psychiatry, 10.1038/s41380-022-01926-8
DNA methylation QTL mapping across diverse human tissues provides molecular links between genetic variation and complex traits
- Kathryn Demanelis, Yihao Lu, Meytal Chernoff, …, Muhammad G Kibriya, Lin S Chen, Brandon L Pierce
- Nat Genet, 10.1038/s41588-022-01248-z
Damaging missense variants in IGF1R implicate a role for IGF-1 resistance in the etiology of type 2 diabetes
- Eugene J Gardner, Katherine A Kentistou, Stasa Stankovic, …, Stephen O’Rahilly, Ken K Ong, John R B Perry
- None, 10.1016/j.xgen.2022.100208
A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk
- Antje K Rottner, Yingying Ye, Elena Navarro-Guerrero, …, Daniel Ebner, Patrick E MacDonald, Anna L Gloyn
- Nat Genet, 10.1038/s41588-022-01261-2
Insight into genetic, biological, and environmental determinants of sexual-dimorphism in type 2 diabetes and glucose-related traits
- Amel Lamri, Monica De Paoli, Russell De Souza, …, Geoff Werstuck, Sonia Anand, Marie Pigeyre
- None, 10.3389/fcvm.2022.964743
Optimized high-throughput screening of non-coding variants identified from genome-wide association studies
- Tunc Morova, Yi Ding, Chia-Chi F Huang, …, Matthew L Freedman, Bogdan Pasaniuc, Nathan A Lack
- Nucleic Acids Res, 10.1093/nar/gkac1198