Inspired by: Eugene Koonin
The evolution of CRISPR-Cas systems in cells.
2023 Articles
526 articles
Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector
- Hongshen Zhao, Qinghua Dong, Hongshen Zhao, …, Hongshen Zhao, Qinghua Dong, Tao Jiang
- Nat Microbiol, 10.1038/s41564-022-01316-4
Structural characterization of the type I-B CRISPR Cas7 from Thermobaculum terrenum
- Pil-Won Seo, Do-Heon Gu, Ji-Won Kim, …, Jun-Hong Kim, Suk-Youl Park, Jeong-Sun Kim
- Biochim Biophys Acta Proteins Proteom, 10.1016/j.bbapap.2023.140900
First full views of a CRISPR-guided system for gene insertion
- Orsolya Barabas, Phoebe A Rice, Orsolya Barabas, …, Phoebe A Rice, Orsolya Barabas, Phoebe A Rice
- Nature, 10.1038/d41586-022-04584-6
Structural snapshots of R-loop formation by a type I-C CRISPR Cascade
- Roisin E O’Brien, Jack P K Bravo, Delisa Ramos, …, Grace N Hibshman, Jacquelyn T Wright, David W Taylor
- Mol Cell, 10.1016/j.molcel.2023.01.024
Structural Basis for the Ribonuclease Activity of a Thermostable CRISPR-Cas13a from Thermoclostridium caenicola
- Feng Wang, Chendi Zhang, Haijiang Xu, …, Wanting Zeng, Lixin Ma, Zhuang Li
- J Mol Biol, 10.1016/j.jmb.2023.168197
Optimized protocols for the characterization of Cas12a activities
- Lindsie Martin, Saadi Rostami, Rakhi Rajan, …, Lindsie Martin, Saadi Rostami, Rakhi Rajan
- Methods Enzymol, 10.1016/bs.mie.2022.08.048
Programmable RNA detection with CRISPR-Cas12a
- Santosh R Rananaware, Emma K Vesco, Grace M Shoemaker, …, Nicolas C Macaluso, Long T Nguyen, Piyush K Jain
- bioRxiv : the preprint server for biology, 10.1101/2023.01.29.525716
Non-canonical inhibition strategies and structural basis of anti-CRISPR proteins targeting type I CRISPR-Cas systems
- Peipei Yin, Yi Zhang, Lingguang Yang, …, Yi Zhang, Lingguang Yang, Yue Feng
- J Mol Biol, 10.1016/j.jmb.2023.167996
Cas12n nucleases, early evolutionary intermediates of type V CRISPR, comprise a distinct family of miniature genome editors
- Weizhong Chen, Jiacheng Ma, Zhaowei Wu, …, Deng Pan, Jin Shi, Quanjiang Ji
- Mol Cell, 10.1016/j.molcel.2023.06.014
Programmable RNA detection with CRISPR-Cas12a
- Santosh R Rananaware, Emma K Vesco, Grace M Shoemaker, …, Nicolas C Macaluso, Long T Nguyen, Piyush K Jain
- Nat Commun, 10.1038/s41467-023-41006-1
2022 Articles
31 articles
Discovery and characterization of novel type I-D CRISPR-guided transposons identified among diverse Tn7-like elements in cyanobacteria
- Shan-Chi Hsieh, Joseph E Peters, Shan-Chi Hsieh, …, Joseph E Peters, Shan-Chi Hsieh, Joseph E Peters
- Nucleic Acids Res, 10.1093/nar/gkac1216
Improved genome editing by an engineered CRISPR-Cas12a
- Enbo Ma, Kai Chen, Honglue Shi, …, Kaihong Zhou, Jinjuan Ye, Jennifer A Doudna
- Nucleic Acids Res, 10.1093/nar/gkac1192
Single Molecule FRET Analysis of CRISPR Cas9 Single Guide RNA Folding Dynamics
- Ikenna C Okafor, Taekjip Ha, Ikenna C Okafor, …, Taekjip Ha, Ikenna C Okafor, Taekjip Ha
- J Phys Chem B, 10.1021/acs.jpcb.2c05428
Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic
- Anna Nemudraia, Artem Nemudryi, Murat Buyukyoruk, …, Kristin S Koutmou, Andrew Santiago-Frangos, Blake Wiedenheft
- Nat Commun, 10.1038/s41467-022-35445-5
Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes
- Daniela S Aliaga Goltsman, Lisa M Alexander, Jyun-Liang Lin, …, Cristina N Butterfield, Brian C Thomas, Christopher T Brown
- Nat Commun, 10.1038/s41467-022-35257-7
A bacterial Argonaute from Tepiditoga spiralis with the ability of RNA guided plasmid cleavage
- Xiaochen Xie, Longyu Wang, Lixin Ma, …, Xiaochen Xie, Longyu Wang, Lixin Ma
- Biochem Biophys Res Commun, 10.1016/j.bbrc.2022.11.097
Miniature CRISPR-Cas12f1-Mediated Single-Nucleotide Microbial Genome Editing Using 3′-Truncated sgRNA
- Ho Joung Lee, Hyun Ju Kim, Sang Jun Lee, …, Ho Joung Lee, Hyun Ju Kim, Sang Jun Lee
- CRISPR J, 10.1089/crispr.2022.0071
CRISPR-Cas13a system: A novel tool for molecular diagnostics
- Lixin Zhao, Minyue Qiu, Xiaojia Li, …, Xiaojia Li, Juanzhen Yang, Jintao Li
- None, 10.3389/fmicb.2022.1060947
Prokaryotic ncRNAs: Master regulators of gene expression
- Rajib Majumder, Sanmitra Ghosh, Arpita Das, …, Saikat Samanta, Abinit Saha, Rudra P Saha
- None, 10.1016/j.crphar.2022.100136
CRISPR-Cas Controls Cryptic Prophages
- Sooyeon Song, Ekaterina Semenova, Konstantin Severinov, …, Michael J Benedik, Toshinari Maeda, Thomas K Wood
- Int J Mol Sci, 10.3390/ijms232416195