The generation of organs that are composed of cells from two or more different species. The term "chimera" historically denotes a mythical creature composed of parts from different animals, and in biology, it is used to describe an organism containing cells or tissues from more than one organism.
2023 Articles
66 articles
Modeling post-implantation stages of human development into early organogenesis with stem-cell-derived peri-gastruloids
- Lizhong Liu, Seiya Oura, Zachary Markham, …, Nicolas Plachta, Gary C Hon, Jun Wu
- Cell, 10.1016/j.cell.2023.07.018
Self-patterning of human stem cells into post-implantation lineages
- Monique Pedroza, Seher Ipek Gassaloglu, Nicolas Dias, …, Helene Kretzmer, Zachary D Smith, Berna Sozen
- Nature, 10.1038/s41586-023-06354-4
In vitro gametogenesis from embryonic stem cells in livestock species: recent advances, opportunities, and challenges to overcome
- Ramon Cesar Botigelli, Carly Guiltinan, Rachel Braz Arcanjo, …, Carly Guiltinan, Rachel Braz Arcanjo, Anna Carolina Denicol
- J Anim Sci, 10.1093/jas/skad137
Human and Pig Pluripotent Stem Cells: From Cellular Products to Organogenesis and Beyond
- Yiyi Xuan, Björn Petersen, Pentao Liu, …, Yiyi Xuan, Björn Petersen, Pentao Liu
- Cells, 10.3390/cells12162075
Towards human organ generation using interspecies blastocyst complementation: Challenges and perspectives for therapy
- Hemanta Sarmah, Anri Sawada, Youngmin Hwang, …, Junichi Tanaka, Kazuhiko Yamada, Munemasa Mori
- None, 10.3389/fcell.2023.1070560
Chimaeras, complementation, and controlling the male germline
- Björn Oback, Daniel A Cossey
- Trends Biotechnol, 10.1016/j.tibtech.2023.03.020
Development of a Method for the In Vivo Generation of Allogeneic Hearts in Chimeric Mouse Embryos
- Konstantina-Maria Founta, Magdalini-Ioanna Tourkodimitri, Zoi Kanaki, …, Zoi Kanaki, Sylvia Bisti, Costis Papanayotou
- Int J Mol Sci, 10.3390/ijms24021163
Derivation of new pluripotent stem cells from human extended pluripotent stem cells with formative features and trophectoderm potential
- Pinmou Zhu, Bohang Zhang, Ruiqi Sun, …, Yiqiang Cui, Jiahao Sha, Yan Yuan
- Cell Prolif, 10.1111/cpr.13480
Organ Regeneration Through Stem Cells and Tissue Engineering
- Laiba Ajmal, Sidra Ajmal, Maleeha Ajmal, …, Sidra Ajmal, Maleeha Ajmal, Gul Nawaz
- None, 10.7759/cureus.34336
Specification of human germ cell fate with enhanced progression capability supported by hindgut organoids
- João Pedro Alves-Lopes, Frederick C K Wong, Walfred W C Tang, …, Geraldine M Jowett, Kirsi Jahnukainen, M Azim Surani
- Cell Rep, 10.1016/j.celrep.2022.111907
2022 Articles
8 articles
Attempts for deriving extended pluripotent stem cells from common marmoset embryonic stem cells
- Sho Yoshimatsu, Mayutaka Nakajima, Iki Sonn, …, Erika Sasaki, Hongkui Deng, Hideyuki Okano
- Genes Cells, 10.1111/gtc.13000
The role of embryonic stem cells, transcription and growth factors in mammals: A review
- Rayees Ahmad Bhat, Humera Rafi, Giuseppe Tardiolo, …, Alessandro Zumbo, Clarisse Coelho, Enrico D’Alessandro
- Tissue Cell, 10.1016/j.tice.2022.102002
Label-free and non-destructive identification of naïve and primed embryonic stem cells based on differences in cellular metabolism
- Kyeong-Mo Koo, Young-Hyun Go, Seong-Min Kim, …, Jeong Tae Do, Tae-Hyung Kim, Hyuk-Jin Cha
- Biomaterials, 10.1016/j.biomaterials.2022.121939
Blastocyst complementation and interspecies chimeras in gene edited pigs
- Yong-Ho Choe, Jacob Sorensen, Daniel J Garry, …, Jacob Sorensen, Daniel J Garry, Mary G Garry
- None, 10.3389/fcell.2022.1065536
Nr6a1 controls Hox expression dynamics and is a master regulator of vertebrate trunk development
- Yi-Cheng Chang, Jan Manent, Jan Schroeder, …, Jose M Polo, Paul Trainor, Edwina McGlinn
- Nat Commun, 10.1038/s41467-022-35303-4
Engineering a functional thyroid as a potential therapeutic substitute for hypothyroidism treatment: A systematic review
- Lei Li, Qixuan Sheng, Huajin Zeng, …, Ming Qiu, Wei Zhang, Chengxiang Shan
- Front Endocrinol (Lausanne), 10.3389/fendo.2022.1065410
Trophectoderm non-coding RNAs reflect the higher metabolic and more invasive properties of young maternal age blastocysts
- Panagiotis Ntostis, Grace Swanson, Georgia Kokkali, …, Helen M Picton, Stephen A Krawetz, David Miller
- Syst Biol Reprod Med, 10.1080/19396368.2022.2153636
Cellular therapies in liver and pancreatic diseases
- Lucia Giuli, Francesco Santopaolo, Maria Pallozzi, …, Gaetano Coppola, Antonio Gasbarrini, Francesca Romana Ponziani
- Dig Liver Dis, 10.1016/j.dld.2022.11.013