Under certain conditions, a cell will exit the cell cycle without dying, instead becoming dormant and ceasing its normal function. This is called cellular senescence. Wikipedia (CC BY-SA 3.0)
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2023 Articles
21 184 articles
Cellular senescence: is the problem a solution for muscle repair?
- José M Izquierdo, José M Izquierdo, José M Izquierdo, José M Izquierdo, José M Izquierdo
- Cell Mol Immunol, 10.1038/s41423-023-00981-7
FAP senescence: a critical event in muscle regeneration
- Xia Kang, Yuqi Gao, So-Ichiro Fukada, …, Yuqi Gao, So-Ichiro Fukada, Hongming Miao
- Signal Transduct Target Ther, 10.1038/s41392-023-01411-w
Senolytics improve muscle adaptation in old mice
- Cory M Dungan, Charlotte A Peterson, Cory M Dungan, …, Charlotte A Peterson, Cory M Dungan, Charlotte A Peterson
- Aging (Albany NY), 10.18632/aging.204578
Synthetic biology, genetic circuits and machine learning: a new age of cancer therapy
- Krishneel Prasad, Ryan S Cross, Misty R Jenkins, …, Krishneel Prasad, Ryan S Cross, Misty R Jenkins
- Mol Oncol, 10.1002/1878-0261.13420
Targeting senescent cells in ageing-related endocrine diseases
- Joshua Stokar, Joshua Stokar
- Nat Rev Endocrinol, 10.1038/s41574-023-00848-x
Spurious transcription may be a hallmark of aging
- Nikita Isima, Nikita Isima, Nikita Isima, Jesús Gil
- Nat Aging, 10.1038/s43587-023-00398-x
Dipping a toe in the fountain of youth
- Arianna Markel, Arianna Markel, Arianna Markel, George Q Daley, Arianna Markel, George Q Daley
- Nat Aging, 10.1038/s43587-022-00188-x
T cell TET2 disruption cuts the breaks on antitumor CAR T cell therapy
- Caitlin C Zebley, Ben Youngblood, Caitlin C Zebley, …, Ben Youngblood, Caitlin C Zebley, Ben Youngblood
- Trends Immunol, 10.1016/j.it.2023.03.008
2022 Articles
2 361 articles
Senescent cells damage the body throughout life
- David J Glass, David J Glass, David J Glass, David J Glass, David J Glass
- Nature, 10.1038/d41586-022-04430-9
Single short reprogramming early in life increases healthspan
- Jean-Marc Lemaitre, Ollivier Milhavet, Ollivier Milhavet, …, Jean-Marc Lemaitre, Ollivier Milhavet, Jean-Marc Lemaitre
- Aging (Albany NY), 10.18632/aging.204457
Identification of Apolipoprotein D as a Dermal Fibroblast Marker of Human Aging for Development of Skin Rejuvenation Therapy
- Kento Takaya, Toru Asou, Kazuo Kishi, …, Kento Takaya, Toru Asou, Kazuo Kishi
- Rejuvenation Res, 10.1089/rej.2022.0056
Senescence induces proteolytically-active PAPP-A secretion and association with extracellular vesicles in human pre-adipocytes
- Cheryl A Conover, Laurie K Bale, Cheryl A Conover, …, Laurie K Bale, Cheryl A Conover, Laurie K Bale
- Exp Gerontol, 10.1016/j.exger.2022.112070
Depletion of growth differentiation factor 15 (GDF15) leads to mitochondrial dysfunction and premature senescence in human dermal fibroblasts
- Sophia Wedel, Ines Martic, Lena Guerrero Navarro, …, Gerhard Pierer, Pidder Jansen-Dürr, Maria Cavinato
- Aging Cell, 10.1111/acel.13752
How a fibroblast ages: a role for bone morphogenetic protein 4 in protecting lung fibroblasts from senescence in pulmonary fibrosis
- Jeffrey C Horowitz, Ana L Mora, Jeffrey C Horowitz, …, Laszlo Farkas, Jeffrey C Horowitz, Ana L Mora
- Eur Respir J, 10.1183/13993003.01702-2022
p21 induces a senescence program and skeletal muscle dysfunction
- Davis A Englund, Alyssa Jolliffe, Zaira Aversa, …, Darren J Baker, Jan M van Deursen, Nathan K LeBrasseur
- Mol Metab, 10.1016/j.molmet.2022.101652
Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression
- Emmanuelle Born, Larissa Lipskaia, Marielle Breau, …, Jean-Michel Flaman, Serge Adnot, Shariq Abid
- Circulation, 10.1161/circulationaha.122.058794
In vitro and in vivo toxicity assessment of the senotherapeutic Peptide 14
- Alessandra Zonari, Lear E Brace, Thuany Alencar-Silva, …, Carolina R Oliveira, Mariana Boroni, Juliana L Carvalho
- None, 10.1016/j.toxrep.2022.07.018
Rapid emergence of transcriptional heterogeneity upon molecular stress predisposes cells to two distinct states of senescence
- Nikolay Burnaevskiy, Junko Oshima, Nikolay Burnaevskiy, …, Nikolay Burnaevskiy, Junko Oshima, Alexander R Mendenhall
- Geroscience, 10.1007/s11357-022-00709-x