Channel: C. elegans RNA epigenetics

Inspired by: Oded Rechavi

Caenorhabditis elegans (/ˌsiːnoʊræbˈdaɪtəs ˈɛləɡæns) is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. This study focuses on the role of RNA molecules in the epigenome and germline in C. elegans. Wikipedia (CC BY-SA 3.0)

    2023 Articles

    847 articles

    Transcriptome-wide analyses of piRNA binding sites suggest distinct mechanisms regulate piRNA binding and silencing in C. elegans

    • Wei-Sheng Wu, Jordan S Brown, Sheng-Cian Shiue, …, Dong-En Lee, Donglei Zhang, Heng-Chi Lee
    • RNA, 10.1261/rna.079441.122
    Comment Section

    The nuclear Argonaute HRDE-1 directs target gene re-localization and shuttles to nuage to promote small RNA-mediated inherited silencing

    • Yue-He Ding, Humberto J Ochoa, Takao Ishidate, …, Takao Ishidate, Masaki Shirayama, Craig C Mello
    • Cell Rep, 10.1016/j.celrep.2023.112408
    Comment Section

    Sensitized piRNA reporter identifies multiple RNA processing factors involved in piRNA-mediated gene silencing

    • Jordan Brown, Donglei Zhang, Wenjun Chen, …, Donglei Zhang, Wenjun Chen, Heng-Chi Lee
    • bioRxiv : the preprint server for biology, 10.1101/2023.01.22.525052
    Comment Section

    Sensitized piRNA reporter identifies multiple RNA processing factors involved in piRNA-mediated gene silencing

    • Jordan Brown, Donglei Zhang, Olivia Gaylord, …, Olivia Gaylord, Wenjun Chen, Heng-Chi Lee
    • Genetics, 10.1093/genetics/iyad095
    Comment Section

    piRNAs regulate a Hedgehog germline-to-soma pro-aging signal

    Comment Section

    Condensate cooperativity underlies transgenerational gene silencing

    Comment Section

    Systematic characterization of small RNAs associated with C. elegans Argonautes

    Comment Section

    The role of RNA-binding proteins in orchestrating germline development in Caenorhabditis elegans

    • Mennatallah M Y Albarqi, Sean P Ryder, Mennatallah M Y Albarqi, …, Sean P Ryder, Mennatallah M Y Albarqi, Sean P Ryder
    • None, 10.3389/fcell.2022.1094295
    Comment Section

    The third barrier to transgenerational inheritance in animals: somatic epigenetic resetting

    • Chee Kiang Ewe, Oded Rechavi, Chee Kiang Ewe, …, Oded Rechavi, Chee Kiang Ewe, Oded Rechavi
    • EMBO Rep, 10.15252/embr.202256615
    Comment Section

    Defining the contribution of microRNA-specific slicing Argonautes in animals

    • Anisha Pal, Vaishnav Vasudevan, François Houle, …, Miguel Quévillon Huberdeau, Allison L Abbott, Martin J Simard
    • bioRxiv : the preprint server for biology, 10.1101/2023.01.19.524781
    Comment Section

    2022 Articles

    93 articles

    Epigenetic dynamics during germline development: insights from Drosophila and C. elegans

    • Ryan J Gleason, Xin Chen, Ryan J Gleason, …, Xin Chen, Ryan J Gleason, Xin Chen
    • Curr Opin Genet Dev, 10.1016/j.gde.2022.102017
    Comment Section

    Hypoxia induces transgenerational epigenetic inheritance of small RNAs

    • Simon Yuan Wang, Kathleen Kim, Zach Klapholz O’Brown, …, Scott G Kennedy, Chaim Chernoff, Eric Lieberman Greer
    • Cell Rep, 10.1016/j.celrep.2022.111800
    Comment Section

    Structural and functional organization of germ plasm condensates

    • Austin Chiappetta, Jeffrey Liao, Siran Tian, …, Jeffrey Liao, Siran Tian, Tatjana Trcek
    • Biochem J, 10.1042/bcj20210815
    Comment Section

    A specific type of Argonaute phosphorylation regulates binding to microRNAs during C. elegans development

    • Miguel Quévillon Huberdeau, Vivek Nilesh Shah, Smita Nahar, …, Helge Großhans, Gunter Meister, Martin J Simard
    • Cell Rep, 10.1016/j.celrep.2022.111822
    Comment Section

    Unscheduled epigenetic modifications cause genome instability and sterility through aberrant R-loops following starvation

    • Bing Sun, McLean Sherrin, Richard Roy, …, Bing Sun, McLean Sherrin, Richard Roy
    • Nucleic Acids Res, 10.1093/nar/gkac1155
    Comment Section

    Safeguarding Drosophila female germ cell identity depends on an H3K9me3 mini domain guided by a ZAD zinc finger protein

    • Laura Shapiro-Kulnane, Micah Selengut, Helen K Salz, …, Laura Shapiro-Kulnane, Micah Selengut, Helen K Salz
    • PLoS Genet, 10.1371/journal.pgen.1010568
    Comment Section

    Mitochondrial genome recovery by ATFS-1 is essential for development after starvation

    Comment Section

    Genetic basis of enhanced stress resistance in long-lived mutants highlights key role of innate immunity in determining longevity

    • Sonja K Soo, Annika Traa, Zenith D Rudich, …, Alibek Moldakozhayev, Meeta Mistry, Jeremy M Van Raamsdonk
    • Aging Cell, 10.1111/acel.13740
    Comment Section

    Maternal Gliadin Intake Reduces Oocyte Quality with Chromosomal Aberrations and Increases Embryonic Lethality through Oxidative Stress in a Caenorhabditis elegans Model

    • Jae Hyuck Lee, Mijin Lee, Hyemin Min, …, Hyemin Min, Esther Youn, Yhong-Hee Shim
    • Nutrients, 10.3390/nu14245403
    Comment Section

    Widespread transposon co-option in the Caenorhabditis germline regulatory network

    • Francesco Nicola Carelli, Chiara Cerrato, Yan Dong, …, Alex Appert, Abby Dernburg, Julie Ahringer
    • Sci Adv, 10.1126/sciadv.abo4082
    Comment Section