In industrial engineering and manufacturing, scalability refers to the capacity of a process, system, or organization to handle a growing workload, adapt to increasing demands, and maintain operational efficiency. A scalable system can effectively manage increased production volumes, new product lines, or expanding markets without compromising quality or performance. Wikipedia (CC BY-SA 3.0)
2023 Articles
422 articles
Characterization of Two Mannitol-Producing Leuconostoc Strains from Pa-Kimchi and Their Application for Juice and Yogurt Fermentation
- Yun Ji Kang, Min Jae Kim, Tae Jin Kim, …, Min Jae Kim, Tae Jin Kim, Jeong Hwan Kim
- J Microbiol Biotechnol, 10.4014/jmb.2301.01015
Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control
- Chien-Ting Li, Richard Eng, Cristal Zuniga, …, Yiqun Chen, Karsten Zengler, Michael J Betenbaugh
- NPJ Syst Biol Appl, 10.1038/s41540-022-00260-7
Developing a metabolic model-based fed-batch feeding strategy for Pichia pastoris fermentation through fine-tuning of the methanol utilization pathway
- Mohammad Amin Boojari, Fatemeh Rajabi Ghaledari, Ehsan Motamedian, …, Ehsan Motamedian, Mehdi Soleimani, Seyed Abbas Shojaosadati
- Microb Biotechnol, 10.1111/1751-7915.14264
Optimal protein production by a synthetic microbial consortium: coexistence, distribution of labor, and syntrophy
- Eugenio Cinquemani, Hidde de Jong, Jean-Luc GouzĂ©, …, Eugenio Cinquemani, Hidde de Jong, Jean-Luc GouzĂ©
- J Math Biol, 10.1007/s00285-023-01935-3
A genome-scale dynamic constraint-based modelling (gDCBM) framework predicts growth dynamics, medium composition and intracellular flux distributions in CHO clonal variations
- Mohammadreza Yasemi, Mario Jolicoeur, Mohammadreza Yasemi, …, Mario Jolicoeur, Mohammadreza Yasemi, Mario Jolicoeur
- Metab Eng, 10.1016/j.ymben.2023.06.005
Transcriptomics and metabolomics analysis of L-phenylalanine overproduction in Escherichia coli
- Wei Sun, Dongqin Ding, Danyang Bai, …, Yaru Zhu, Cuiying Zhang, Dawei Zhang
- Microb Cell Fact, 10.1186/s12934-023-02070-w
Tuning metabolic efficiency for increased product yield in high titer fed-batch Chinese hamster ovary cell culture
- Apolline Helfer, Sylvain Gros, Dave Kolwyck, …, Sylvain Gros, Dave Kolwyck, Daniel J Karst
- Biotechnol Prog, 10.1002/btpr.3327
Is heterogeneity in large-scale bioreactors a real problem in recombinant protein synthesis by Pichia pastoris?
- Edgar Velastegui, Johan Quezada, Karlo Guerrero, …, Juan Andres Martinez, Julio Berrios, Patrick Fickers
- Appl Microbiol Biotechnol, 10.1007/s00253-023-12434-2
“Organized stress” for robust scale-up of intensified production process with fed-batch seed bioreactor
- Bassem Ben Yahia, Antoine Piednoir, Thomas Dahomais, …, Thomas Dahomais, Stefanie Eggermont, Wolfgang Paul
- Biotechnol Bioeng, 10.1002/bit.28396
Metabolic engineering of fast-growing Vibrio natriegens for efficient pyruvate production
- Fengli Wu, Shucai Wang, Yanfeng Peng, …, Yanfeng Peng, Yufeng Guo, Qinhong Wang
- Microb Cell Fact, 10.1186/s12934-023-02185-0
2022 Articles
54 articles
Applying intensified design of experiments to mammalian cell culture processes
- Verena Nold, Lisa Junghans, Lorenzo Bisgen, …, Thomas Schwab, Bettina Knapp, Stefan Wieschalka
- None, 10.1002/elsc.202100123
High-efficiency production of 5-hydroxyectoine using metabolically engineered Corynebacterium glutamicum
- Lukas Jungmann, Sarah Lisa Hoffmann, Caroline Lang, …, Judith Becker, Michael Kohlstedt, Christoph Wittmann
- Microb Cell Fact, 10.1186/s12934-022-02003-z
Current advances of Pichia pastoris as cell factories for production of recombinant proteins
- Yingjie Pan, Jiao Yang, Jianping Wu, …, Jianping Wu, Lirong Yang, Hao Fang
- None, 10.3389/fmicb.2022.1059777
Developing methylotrophic microbial platforms for a methanol-based bioindustry
- Hawaibam Birla Singh, Min-Kyoung Kang, Moonhyuk Kwon, …, Min-Kyoung Kang, Moonhyuk Kwon, Seon-Won Kim
- None, 10.3389/fbioe.2022.1050740
Analysis of the Propionate Metabolism in Bacillus subtilis during 3-Indolacetic Production
- Freddy Castillo-Alfonso, Alejandro Quintana-MenĂ©ndez, Gabriel Vigueras-RamĂrez, …, Alfonso Mauricio Sales-Cruz, Luis Manuel Rosales-Colunga, Roberto Olivares-HernĂĄndez
- None, 10.3390/microorganisms10122352
Metabolic engineering of Corynebacterium glutamicum for l-tyrosine production from glucose and xylose
- Eldin KurpejoviÄ, Arthur Burgardt, GĂŒlsĂŒm Merve Bastem, …, Nora Junker, Volker F Wendisch, Berna Sariyar Akbulut
- J Biotechnol, 10.1016/j.jbiotec.2022.12.005
Engineering isoprenoids production in metabolically versatile microbial host Pseudomonas putida
- Xi Wang, Edward E K Baidoo, Ramu Kakumanu, …, Silvia Xie, Aindrila Mukhopadhyay, Taek Soon Lee
- None, 10.1186/s13068-022-02235-6
Synthetic biology of extremophiles: a new wave of biomanufacturing
- Jian-Wen Ye, Yi-Na Lin, Xue-Qing Yi, …, Zhuo-Xuan Yu, Xu Liu, Guo-Qiang Chen
- Trends Biotechnol, 10.1016/j.tibtech.2022.11.010
Metabolic Engineering: Methodologies and Applications
- Michael J Volk, Vinh G Tran, Shih-I Tan, …, Pu Xue, Teresa A Martin, Huimin Zhao
- Chem Rev, 10.1021/acs.chemrev.2c00403
The Production of Pyruvate in Biological Technology: A Critical Review
- Wei Yuan, Yongbao Du, Kechen Yu, …, Yuanyuan Yang, Yinjun Zhang, Jie Sun
- None, 10.3390/microorganisms10122454