A biosensor is an analytical device, used for the detection of a chemical substance, that combines a biological component with a physicochemical detector. The sensitive biological element, e.g. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc., is a biologically derived material or biomimetic component that interacts with, binds with, or recognizes the analyte under study. The biologically sensitive elements can also be created by biological engineering. The transducer or the detector element, which transforms one signal into another one, works in a physicochemical way: optical, piezoelectric, electrochemical, electrochemiluminescence etc., resulting from the interaction of the analyte with the biological element, to easily measure and quantify. Wikipedia (CC BY-SA 3.0)
2023 Articles
504 articles
Adaptable, Turn-On Monobody (ATOM) Fluorescent Biosensors for Multiplexed Detection in Cells
- Harsimranjit Sekhon, Jeung-Hoi Ha, Maria F Presti, …, Paige O Mirsky, Anna M John, Stewart N Loh
- bioRxiv : the preprint server for biology, 10.1101/2023.03.28.534597
Maximizing the performance of protein-based fluorescent biosensors
- Fu Chai, Dazhou Cheng, Yusuke Nasu, …, Yusuke Nasu, Takuya Terai, Robert E Campbell
- Biochem Soc Trans, 10.1042/bst20221413
Research Progresses and Applications of Fluorescent Protein Antibodies: A Review Focusing on Nanobodies
- Yu-Lei Chen, Xin-Xin Xie, Ning Zhong, …, Ling Weng, Tengchuan Jin, Min-Jie Cao
- Int J Mol Sci, 10.3390/ijms24054307
Fluorescent proteins and genetically encoded biosensors
- Minji Wang, Yifan Da, Yang Tian, …, Minji Wang, Yifan Da, Yang Tian
- Chem Soc Rev, 10.1039/d2cs00419d
Ultrafast fluorescence depolarisation in green fluorescence protein tandem dimers as hydrophobic environment sensitive probes
- Alejandro Sánchez-Pedreño Jiménez, Henry L Puhl, Steven S Vogel, Youngchan Kim
- Phys Chem Chem Phys, 10.1039/d3cp01765f
Biosensor Optimization Using a Förster Resonance Energy Transfer Pair Based on mScarlet Red Fluorescent Protein and an mScarlet-Derived Green Fluorescent Protein
- Khyati Gohil, Sheng-Yi Wu, Kei Takahashi-Yamashiro, …, Kei Takahashi-Yamashiro, Yi Shen, Robert E Campbell
- ACS Sens, 10.1021/acssensors.2c01730
A general method for the development of multicolor biosensors with large dynamic ranges
- Lars Hellweg, Anna Edenhofer, Lucas Barck, …, Birgit Koch, Kai Johnsson, Julien Hiblot
- Nat Chem Biol, 10.1038/s41589-023-01350-1
Development of green fluorescent protein-based cAMP indicators for covering a wide range of cAMP concentrations
- Sohei Hiasa, Takeru Fujimori, Saki Aiki, …, Hiroshi Ueda, Takashi Tsuboi, Tetsuya Kitaguchi
- None, 10.1039/d3ra01390a
Blue-to-Red TagFT, mTagFT, mTsFT, and Green-to-FarRed mNeptusFT2 Proteins, Genetically Encoded True and Tandem Fluorescent Timers
- Oksana M Subach, Anna V Vlaskina, Yulia K Agapova, …, Maxim V Patrushev, Konstantin M Boyko, Fedor V Subach
- Int J Mol Sci, 10.3390/ijms24043279
Fast and sensitive GCaMP calcium indicators for neuronal imaging
- Yan Zhang, Loren L Looger, Yan Zhang, Loren L Looger
- J Physiol, 10.1113/jp283832
2022 Articles
54 articles
Smart genetically-encoded biosensors for the chemical monitoring of living systems
- Toon Van Thillo, Vincent Van Deuren, Peter Dedecker
- Chem Commun (Camb), 10.1039/d2cc05363b
Discovery of a monomeric green fluorescent protein sensor for chloride by structure-guided bioinformatics
- Weicheng Peng, Caden C Maydew, Hiu Kam, …, Sameera Abeyrathna, Gabriele Meloni, Sheel C Dodani
- None, 10.1039/d2sc03903f
Modular Peroxidase-Based Reporters for Detecting Protease Activity and Protein Interactions with Temporal Gating
- Guanwei Zhou, Wei Wei Wan, Wenjing Wang, …, Guanwei Zhou, Wei Wei Wan, Wenjing Wang
- J Am Chem Soc, 10.1021/jacs.2c08280
Elastic Fluorescent Protein-Based Down-Converting Optical Films for Flexible Display
- Butaek Lim, Jinyeong Kim, Malav S Desai, …, Weiyu Wu, Inseok Chae, Seung-Wuk Lee
- Biomacromolecules, 10.1021/acs.biomac.2c00957
Advances in the Computational Design of Small-Molecule-Controlled Protein-Based Circuits for Synthetic Biology
- Simon Kretschmer, Tanja Kortemme, Simon Kretschmer, Tanja Kortemme, Simon Kretschmer, Tanja Kortemme
- None, 10.1109/jproc.2022.3157898
Reporter gene systems: A powerful tool for Leishmania studies
- Romário Lopes Boy, Ahyun Hong, Juliana Ide Aoki, …, Juliana Ide Aoki, Lucile Maria Floeter-Winter, Maria Fernanda Laranjeira-Silva
- None, 10.1016/j.crmicr.2022.100165
Conformational Dynamics of mCherry Variants: A Link between Side-Chain Motions and Fluorescence Brightness
- Srijit Mukherjee, Premashis Manna, Nancy Douglas, …, Nancy Douglas, Prem P Chapagain, Ralph Jimenez
- J Phys Chem B, 10.1021/acs.jpcb.2c05584
A novel aptamer beacon for rapid screening of recombinant cells and in vivo monitoring of recombinant proteins
- Wei-Wei Zheng, Li-Ting Yang, Hang Zhou, …, Jing Chen, Cai-Wen Duan, Kai-Ming Chen
- Appl Microbiol Biotechnol, 10.1007/s00253-022-12331-0
A Dual Fluorescence Assay Enables High-Throughput Screening for Poly(ethylene terephthalate) Hydrolases
- Kun Liu, Ziping Xu, Zhiyi Zhao, …, Yating Chai, Li Ma, Shengying Li
- ChemSusChem, 10.1002/cssc.202202019
A Selective Fluorescent l-Lactate Biosensor Based on an l-Lactate-Specific Transcription Regulator and Förster Resonance Energy Transfer
- Xianzhi Xu, Rong Xu, Shuang Hou, …, Ping Xu, Chao Gao, Cuiqing Ma
- Biosensors (Basel), 10.3390/bios12121111