Channel: Biohalogenation

Inspired by: Pablo I Nikel

Biohalogenation refers to the biological process by which halogens (fluorine, chlorine, bromine, iodine, and astatine) are introduced into organic compounds by living organisms. This process can be found in various organisms, including bacteria, fungi, and certain marine organisms. The resulting halogenated organic compounds can serve various biological functions and can range from simple molecules to complex natural products. ChatGPT (CC BY 4.0)

2023 Articles

66 articles

Enzymatic Halogenation of Terminal Alkynes

  • April L Lukowski, Felix M Hubert, Thuan-Ethan Ngo, …, Nicole E Avalon, William H Gerwick, Bradley S Moore
  • J Am Chem Soc, 10.1021/jacs.3c05750
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Enabling Peroxygenase Activity in Cytochrome P450 Monooxygenases by Engineering Hydrogen Peroxide Tunnels

  • Panxia Zhao, Fanhui Kong, Yiping Jiang, …, Xiangquan Qin, Xiaoxia Tian, Zhiqi Cong
  • J Am Chem Soc, 10.1021/jacs.3c00195
Comment Section

Structure of the green heme isolated from allylbenzene-modified chloroperoxidase: A novel heme architecture implicating the mechanisms of CPO inactivation and epoxidation

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The Chlamydia trachomatis p-aminobenzoate synthase CADD is a manganese-dependent oxygenase that uses its own amino acid residues as substrates

  • Rowan Wooldridge, Spenser Stone, Andrew Pedraza, …, W Keith Ray, Richard F Helm, Kylie D Allen
  • FEBS Lett, 10.1002/1873-3468.14573
Comment Section

Enzyme function prediction using contrastive learning

  • Tianhao Yu, Haiyang Cui, Jianan Canal Li, …, Yunan Luo, Guangde Jiang, Huimin Zhao
  • Science, 10.1126/science.adf2465
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Solvent isotope effects in the catalytic cycle of P450 CYP17A1: Computational modeling of the hydroxylation and lyase reactions

  • Ilia G Denisov, Stephen G Sligar, Ilia G Denisov, …, Stephen G Sligar, Ilia G Denisov, Stephen G Sligar
  • J Inorg Biochem, 10.1016/j.jinorgbio.2023.112202
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Compound I Formation and Reactivity in Dimeric Chlorite Dismutase: Impact of pH and the Dynamics of the Catalytic Arginine

  • Daniel Schmidt, Nikolaus Falb, Ilenia Serra, …, Gianantonio Battistuzzi, Paul G Furtmüller, Christian Obinger
  • Biochemistry, 10.1021/acs.biochem.2c00696
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Hijacking Chemical Reactions of P450 Enzymes for Altered Chemical Reactions and Asymmetric Synthesis

  • Eerappa Rajakumara, Dubey Saniya, Priyanka Bajaj, …, Rajanna Rajeshwari, Jyotsnendu Giri, Mehdi D Davari
  • Int J Mol Sci, 10.3390/ijms24010214
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Valorization of bioethanol by-products to produce unspecific peroxygenase with Agrocybe aegerita: Technological and proteomic perspectives

  • Sandra González-Rodríguez, Alba Trueba-Santiso, Thelmo A Lu-Chau, …, Thelmo A Lu-Chau, María Teresa Moreira, Gemma Eibes
  • N Biotechnol, 10.1016/j.nbt.2023.05.001
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Rieske Oxygenases and Other Ferredoxin-Dependent Enzymes: Electron Transfer Principles and Catalytic Capabilities

  • Michael Ernst Runda, Niels A W de Kok, Sandy Schmidt, …, Michael E Runda, Niels A W de Kok, Sandy Schmidt
  • Chembiochem, 10.1002/cbic.202300078
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2022 Articles

5 articles

Effect of attaching hydrophilic oligopeptides to the C-terminus of organic solvent-tolerant metal-free bromoperoxidase BPO-A1 from Streptomyces aureofaciens on organic solvent-stability

  • Hideyasu China, Hiroyasu Ogino, Hideyasu China, …, Hiroyasu Ogino, Hideyasu China, Hiroyasu Ogino
  • Biochem Biophys Res Commun, 10.1016/j.bbrc.2022.12.012
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Na,K-ATPase: A murzyme facilitating thermodynamic equilibriums at the membrane-interface

  • Kelath Murali Manoj, Daniel A Gideon, Nikolai M Bazhin, …, Vijay Nirusimhan, Mahendra Kavdia, Laurent Jaeken
  • J Cell Physiol, 10.1002/jcp.30925
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Comparative oxidative ability of mononuclear and dinuclear high-valent iron-oxo species towards the activation of methane: does the axial/bridge atom modulate the reactivity?

  • Mursaleem Ansari, Mursaleem Ansari, Mursaleem Ansari, Gopalan Rajaraman
  • Dalton Trans, 10.1039/d2dt02559k
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Chemical, physical, and biological stimuli-responsive nanogels for biomedical applications (mechanisms, concepts, and advancements): A review

  • Sachin Bhaladhare, Sulagna Bhattacharjee, Sachin Bhaladhare, …, Sulagna Bhattacharjee, Sachin Bhaladhare, Sulagna Bhattacharjee
  • Int J Biol Macromol, 10.1016/j.ijbiomac.2022.12.076
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Anti-Infective and Toxicity Properties of Carbon Based Materials: Graphene and Functionalized Carbon Nanotubes

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