Channel: Bacterial metabolic models

Inspired by: Bernhard Ø Palsson

Metabolic network modelling, also known as metabolic network reconstruction or metabolic pathway analysis, allows for an in-depth insight into the molecular mechanisms of bacteria. In particular, these models correlate the genome with molecular physiology. Wikipedia (CC BY-SA 3.0)

2023 Articles

14 289 articles

The effective deficiency of biochemical networks

  • Damoun Langary, Anika Küken, Zoran Nikoloski, …, Damoun Langary, Anika Küken, Zoran Nikoloski
  • Sci Rep, 10.1038/s41598-023-41767-1
Comment Section

CAVE: a cloud-based platform for analysis and visualization of metabolic pathways

  • Zhitao Mao, Qianqian Yuan, Haoran Li, …, Shihui Yang, Xiaoping Liao, Hongwu Ma
  • Nucleic Acids Res, 10.1093/nar/gkad360
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Sensitivity Analysis of Genome-Scale Metabolic Flux Prediction

  • Puhua Niu, Maria J Soto, Shuai Huang, …, Francis J Alexander, Ian Blaby, Xiaoning Qian
  • J Comput Biol, 10.1089/cmb.2022.0368
Comment Section

Gene Deletion Algorithms for Minimum Reaction Network Design by Mixed-Integer Linear Programming for Metabolite Production in Constraint-Based Models: gDel_minRN

  • Takeyuki Tamura, Ai Muto-Fujita, Yukako Tohsato, …, Ai Muto-Fujita, Yukako Tohsato, Tomoyuki Kosaka
  • J Comput Biol, 10.1089/cmb.2022.0352
Comment Section

CONTRABASS: exploiting flux constraints in genome-scale models for the detection of vulnerabilities

  • Alexandru Oarga, Bridget P Bannerman, Jorge Júlvez, …, Alexandru Oarga, Bridget P Bannerman, Jorge Júlvez
  • Bioinformatics, 10.1093/bioinformatics/btad053
Comment Section

Model-driven experimental design workflow expands understanding of regulatory role of Nac in Escherichia coli

  • Joon Young Park, Sang-Mok Lee, Ali Ebrahim, …, Sang Woo Seo, Bernhard O Palsson, Donghyuk Kim
  • None, 10.1093/nargab/lqad006
Comment Section

On the geometry of elementary flux modes

  • Frederik Wieder, Martin Henk, Frederik Wieder, …, Frederik Wieder, Martin Henk, Alexander Bockmayr
  • J Math Biol, 10.1007/s00285-023-01982-w
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Prediction of Metabolic Flux Distribution by Flux Sampling: As a Case Study, Acetate Production from Glucose in Escherichia coli

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Mitigating biomass composition uncertainties in flux balance analysis using ensemble representations

  • Yoon-Mi Choi, Dong-Hyuk Choi, Yi Qing Lee, …, Nathan E Lewis, Meiyappan Lakshmanan, Dong-Yup Lee
  • None, 10.1016/j.csbj.2023.07.025
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FBA-PRCC. Partial Rank Correlation Coefficient (PRCC) Global Sensitivity Analysis (GSA) in Application to Constraint-Based Models

  • Anatoly Sorokin, Igor Goryanin, Anatoly Sorokin, Igor Goryanin, Anatoly Sorokin, Igor Goryanin
  • Biomolecules, 10.3390/biom13030500
Comment Section

2022 Articles

1 418 articles

High-quality genome-scale metabolic network reconstruction of probiotic bacterium Escherichia coli Nissle 1917

  • Max van ‘t Hof, Omkar S Mohite, Jonathan M Monk, …, Tilmann Weber, Bernhard O Palsson, Morten O A Sommer
  • BMC Bioinformatics, 10.1186/s12859-022-05108-9
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Modeling the metabolic dynamics at the genome-scale by optimized yield analysis

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Guidelines for extracting biologically relevant context-specific metabolic models using gene expression data

  • Saratram Gopalakrishnan, Chintan J Joshi, Miguel Valderrama Gomez, …, William Johnson, Cleo Kontoravdi, Nathan E Lewis
  • Metab Eng, 10.1016/j.ymben.2022.12.003
Comment Section

Analysis of the Propionate Metabolism in Bacillus subtilis during 3-Indolacetic Production

  • Freddy Castillo-Alfonso, Alejandro Quintana-Menéndez, Gabriel Vigueras-Ramírez, …, Alfonso Mauricio Sales-Cruz, Luis Manuel Rosales-Colunga, Roberto Olivares-Hernández
  • None, 10.3390/microorganisms10122352
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Machine learning-guided prediction of potential engineering targets for microbial production of lycopene

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Navigating and expanding the roadmap of natural product genome mining tools

  • Friederike Biermann, Sebastian L Wenski, Eric J N Helfrich, Friederike Biermann, Sebastian L Wenski, Eric J N Helfrich
  • None, 10.3762/bjoc.18.178
Comment Section

An improved algorithm for flux variability analysis

  • Dustin Kenefake, Erick Armingol, Nathan E Lewis, …, Erick Armingol, Nathan E Lewis, Efstratios N Pistikopoulos
  • BMC Bioinformatics, 10.1186/s12859-022-05089-9
Comment Section

Predicting stress response and improved protein overproduction in Bacillus subtilis

  • Juan D Tibocha-Bonilla, Cristal Zuñiga, Asama Lekbua, …, Kevin Rychel, Katie Short, Karsten Zengler
  • NPJ Syst Biol Appl, 10.1038/s41540-022-00259-0
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Systems Biology: New Insight into Antibiotic Resistance

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