Channel: Ancient DNA sequencing

Ancient DNA (aDNA) is DNA isolated from ancient specimens. Due to degradation processes (including cross-linking, deamination and fragmentation) ancient DNA is more degraded in comparison with contemporary genetic material. Even under the best preservation conditions, there is an upper boundary of 0.4–1.5 million years for a sample to contain sufficient DNA for sequencing technologies. Wikipedia (CC BY-SA 3.0)

2023 Articles

77 363 articles

Human populations are not biologically and genetically discrete

  • Martin S Fischer, Johannes Krause, Martin S Fischer, …, Johannes Krause, Martin S Fischer, Johannes Krause
  • Br J Psychol, 10.1111/bjop.12635
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Human DNA from a prehistoric artefact

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Huge broad-bean genome could improve yields of an underused crop

  • Eric J B von Wettberg, Azalea Guerra-Garcia, Eric J B von Wettberg, …, Azalea Guerra-Garcia, Eric J B von Wettberg, Azalea Guerra-Garcia
  • Nature, 10.1038/d41586-023-00461-y
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[Multiple loci account for human height]

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Ancient genomes show how humans escaped Europe’s deep freeze

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Advancing artificial intelligence to help feed the world

  • Ben J Hayes, Chensong Chen, Owen Powell, …, Kira Villiers, Kathryn E Kemper, Lee T Hickey
  • Nat Biotechnol, 10.1038/s41587-023-01898-2
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Bubonic Plague Protector Shows Its Dark Side

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Genomics expands the mammalverse

  • Nathan S Upham, Michael J Landis, Nathan S Upham, …, Michael J Landis, Nathan S Upham, Michael J Landis
  • Science, 10.1126/science.add2209
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New genes on the block: Neofunctionalization of tandem duplicate genes with putative new functions in Arabidopsis

  • José Manuel Ugalde, Henryk Straube, José Manuel Ugalde, …, Henryk Straube, José Manuel Ugalde, Henryk Straube
  • Plant Physiol, 10.1093/plphys/kiad271
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Ötzi the Iceman has a new look: balding and dark-skinned

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2022 Articles

8 746 articles

Analysis of Ancient Microbial DNA

  • Olivier Gorgé, E Andrew Bennett, Diyendo Massilani, …, Julien Daligault, Eva-Maria Geigl, Thierry Grange
  • Methods Mol Biol, 10.1007/978-1-0716-2871-3_6
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Three assays for in-solution enrichment of ancient human DNA at more than a million SNPs

  • Nadin Rohland, Swapan Mallick, Matthew Mah, …, Robert Maier, Nick Patterson, David Reich
  • Genome Res, 10.1101/gr.276728.122
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Ancient DNA from Protohistoric Period Cambodia indicates that South Asians admixed with local populations as early as 1st-3rd centuries CE

  • Piya Changmai, Ron Pinhasi, Michael Pietrusewsky, …, Rona Michi Ikehara-Quebral, David Reich, Pavel Flegontov
  • Sci Rep, 10.1038/s41598-022-26799-3
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CONGA: Copy number variation genotyping in ancient genomes and low-coverage sequencing data

  • Arda Söylev, Sevim Seda Çokoglu, Dilek Koptekin, …, Dilek Koptekin, Can Alkan, Mehmet Somel
  • PLoS Comput Biol, 10.1371/journal.pcbi.1010788
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Genetic admixture and language shift in the medieval Volga-Oka interfluve

  • Sanni Peltola, Kerttu Majander, Nikolaj Makarov, …, Kerkko Nordqvist, Elina Salmela, Päivi Onkamo
  • Curr Biol, 10.1016/j.cub.2022.11.036
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Kinship practices in the early state El Argar society from Bronze Age Iberia

  • Camila Oliart, Cristina Rihuete-Herrada, Adam B Rohrlach, …, Rafael Micó, Roberto Risch, Wolfgang Haak
  • Sci Rep, 10.1038/s41598-022-25975-9
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Unraveling Signatures of Local Adaptation among Indigenous Groups from Mexico

  • Humberto García-Ortiz, Francisco Barajas-Olmos, Cecilia Contreras-Cubas, …, Augusto Rojas-Martínez, Angélica Martínez-Hernández, Lorena Orozco
  • Genes (Basel), 10.3390/genes13122251
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Modeling the spatiotemporal spread of beneficial alleles using ancient genomes

  • Rasa A Muktupavela, Martin Petr, Laure Ségurel, …, Thorfinn Korneliussen, John Novembre, Fernando Racimo
  • Elife, 10.7554/elife.73767
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Maternal genetic diversity of ancient goats in Finland and Estonia and comparison with extant northern European goat breeds

  • Eve Rannamäe, Urmas Saarma, Juha Kantanen, …, Urmas Saarma, Juha Kantanen, Auli Bläuer
  • Anim Genet, 10.1111/age.13281
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