Different tissues and the cells they consist of need to orchestrate their work in a tightly controlled manner so that the organism as a whole can function. One of the main ways this is achieved is through excreting signal molecules into the blood where they make their way to other tissues, affecting their behavior. The profile of these molecules changes as we age. Wikipedia (CC BY-SA 3.0)
2023 Articles
143 471 articles
GDF-11 as a Potential Cardiac Pro-Angiogenic Factor
- Tomohiro Kato, Richard T Lee, Tomohiro Kato, Richard T Lee, Tomohiro Kato, Richard T Lee
- None, 10.1016/j.jacbts.2023.04.003
What the Stanford president’s resignation can teach lab leaders
- Max Kozlov, Max Kozlov
- Nature, 10.1038/d41586-023-02438-3
Clonal hematopoiesis and ischemic stroke
- Nan Wang, Alan R Tall, Nan Wang, …, Alan R Tall, Nan Wang, Alan R Tall
- Blood, 10.1182/blood.2022019177
Aging gracefully: time and space matter
- Charline Roy, Laurent Molin, Florence Solari, …, Charline Roy, Laurent Molin, Florence Solari
- Aging (Albany NY), 10.18632/aging.204773
The main protease of SARS-CoV-2 downregulates innate immunity via a translational repression
- Weifeng Liang, Ming Gu, Lingxiang Zhu, …, Subodh Kumar Samrat, Jiapeng Zhu, Yin Chen
- Signal Transduct Target Ther, 10.1038/s41392-023-01418-3
Variability in MUC5B Expression Is Dependent on Genotype and Endotype in Idiopathic Pulmonary Fibrosis
- Auyon J Ghosh, Matthew Moll, Brian D Hobbs, …, Edwin K Silverman, Ivana V Yang, Craig P Hersh
- Am J Respir Crit Care Med, 10.1164/rccm.202209-1835le
Resilient brains run out of (c)GAS
- Andrea Francesca M Salvador, Andrea Francesca M Salvador, Andrea Francesca M Salvador, …, Jonathan Kipnis, Andrea Francesca M Salvador, Jonathan Kipnis
- Nat Immunol, 10.1038/s41590-023-01485-2
Transferrin receptor 1: keeper of HFE
- Nermi L Parrow, Robert E Fleming, Nermi L Parrow, …, Robert E Fleming, Nermi L Parrow, Robert E Fleming
- Blood, 10.1182/blood.2022018740
Hunger potentiated
- Connor Laule, Deniz Atasoy, Connor Laule, …, Deniz Atasoy, Connor Laule, Deniz Atasoy
- Cell Metab, 10.1016/j.cmet.2023.04.005
Synthetic biology, genetic circuits and machine learning: a new age of cancer therapy
- Krishneel Prasad, Ryan S Cross, Misty R Jenkins, …, Krishneel Prasad, Ryan S Cross, Misty R Jenkins
- Mol Oncol, 10.1002/1878-0261.13420
2022 Articles
17 066 articles
Response by Sedej and Abdellatif to Letter Regarding Article, “Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity”
- Simon Sedej, Mahmoud Abdellatif, Simon Sedej, Mahmoud Abdellatif, Simon Sedej, Mahmoud Abdellatif
- Circulation, 10.1161/circulationaha.122.062496
Gutsy sensations modulate intestinal disease
- Wang Cao, Gabrielle Belz, Wang Cao, …, Gabrielle Belz, Wang Cao, Gabrielle Belz
- Trends Immunol, 10.1016/j.it.2022.11.007
How a fibroblast ages: a role for bone morphogenetic protein 4 in protecting lung fibroblasts from senescence in pulmonary fibrosis
- Jeffrey C Horowitz, Ana L Mora, Jeffrey C Horowitz, …, Laszlo Farkas, Jeffrey C Horowitz, Ana L Mora
- Eur Respir J, 10.1183/13993003.01702-2022
Depletion of growth differentiation factor 15 (GDF15) leads to mitochondrial dysfunction and premature senescence in human dermal fibroblasts
- Sophia Wedel, Ines Martic, Lena Guerrero Navarro, …, Gerhard Pierer, Pidder Jansen-Dürr, Maria Cavinato
- Aging Cell, 10.1111/acel.13752
The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
- Wendao Liu, Xiaohua Ye, Zhiqiang An, …, Xiaohua Ye, Zhiqiang An, Zhongming Zhao
- Virol J, 10.1186/s12985-022-01923-x
Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection
- Leon Cords, Robin Woost, Silke Kummer, …, Marylyn M Addo, Julian Schulze Zur Wiesch, Claudia Beisel
- Cytokine, 10.1016/j.cyto.2022.156109
Senescence induces proteolytically-active PAPP-A secretion and association with extracellular vesicles in human pre-adipocytes
- Cheryl A Conover, Laurie K Bale, Cheryl A Conover, …, Laurie K Bale, Cheryl A Conover, Laurie K Bale
- Exp Gerontol, 10.1016/j.exger.2022.112070
Energy intake at the intersection of the clock and ageing
- Kristin Eckel-Mahan, Kristin Eckel-Mahan
- Nat Rev Endocrinol, 10.1038/s41574-022-00791-3
Cenicriviroc for the treatment of COVID-19: first interim results of a randomised, placebo-controlled, investigator-initiated, double-blind phase II trial
- Florian Kurth, Elisa T Helbig, Lena J Lippert, …, Leif E Sander, Christoph Jochum, Frank Tacke
- J Glob Antimicrob Resist, 10.1016/j.jgar.2022.12.004
Dickkopf-1 drives tumor immune evasion by inducing PD-L1 expression in hepatocellular carcinoma
- Ruo-Han Yang, Jia Qin, Jin-Lan Cao, …, Meng-Qing Wang, Dong Fang, Song-Qiang Xie
- Biochem Pharmacol, 10.1016/j.bcp.2022.115378