Reformulation of an extant ATPase active site to mimic ancestral GTPase activity reveals a nucleotide base requirement for function

eLife

Taylor B Updegrove, Jailynn Harke, Vivek Anantharaman, …, Jue D Wang, L Aravind, Kumaran S Ramamurthi

• DOI: 10.7554/elife.65845
• PMID: 33704064
• PMCID: PMC7952092