Oral IRAK-4 Inhibitor CA-4948 Is Blood-Brain Barrier Penetrant and Has Single-Agent Activity against CNS Lymphoma and Melanoma Brain Metastases

Clinical cancer research : an official journal of the American Association for Cancer Research

Christina Von Roemeling, Bently P Doonan, Kelena Klippel, …, Abhisheak Sharma, Han W Tun, Duane A Mitchell

• DOI: 10.1158/1078-0432.ccr-22-1682
• PMID: 36749885
• PMCID: PMC10150246