Arnold World February 2023

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bioRxiv

Microbial sensor variation across biogeochemical conditions in the terrestrial deep subsurface

2023-02-02

DOI:10.1101/2023.02.01.526704

A. L. Goldman, E. M. Fulk, L. Momper, C. Heider, J. Mulligan, M. R. Osburn, C. A. Masiello, J. J. Silberg

Affiliations

Rice University

A big congrats to Annelise (@agoldman252), Emm Fulk, @biogeochem, and @ProfMaggie for their study showing that microbial sensor abundances correlate with biogeochemical conditions https://doi.org/10.1101/2023.02.01.526704…

2023-02-03

So happy to share my first ever paper with the world, in which we looked at relationships between microbial sensor proteins and environmental conditions in the deep subsurface! Thank you so much to Emm, @JoffSilberg @biogeochem and @ProfMaggie for all their ideas and support

2023-02-03

synbio-meteng

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Analytical chemistry

Mass Spectrometry-Based High-Throughput Quantification of Bioproducts in Liquid Culture.

2023-02-15

PubMed:36790390; DOI:10.1021/acs.analchem.2c04845

Shuaizhen Zhou¹, Zia Fatma¹, Pu Xue¹, Shekhar Mishra¹, Mingfeng Cao¹, Huimin Zhao¹, Jonathan V Sweedler¹

Affiliations

Department of Energy Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

A #CABBI team at @UofIllinois demonstrated a fast and accurate quantitative screening approach for multiple microbial metabolites across different #yeast strains & mediums, further enabling high-throughput metabolic engineering of yeasts.

Paper:
https://pubs.acs.org/doi/10.1021/acs.analchem.2c04845…

2023-03-28

Chemistry (Weinheim an der Bergstrasse, Germany)

Precise Control of Dissipative Self-assembly by Light and Electricity.

2023-02-03

PubMed:36737408; DOI:10.1002/chem.202300347

Chunfeng Chen¹, Zhibin Guan¹

Affiliations

Department of Chemistry, University of California Irvine, Irvine, California, 92697, United States

Precise Control of Dissipative Self-assembly by Light and Electricity (Chen and Guan) https://onlinelibrary.wiley.com/doi/10.1002/chem.202300347…

2023-04-18

ACS synthetic biology

CMI: CRISPR/Cas9 Based Efficient Multiplexed Integration in Saccharomyces cerevisiae .

2023-02-28

PubMed:36853024; DOI:10.1021/acssynbio.2c00591

Jie Meng¹, Yue Qiu¹, Yueping Zhang², Huimin Zhao³, Shuobo Shi¹

Affiliations

Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China
College of Veterinary Medicine, China Agricultural University, Beijing 100193, China
Department of Chemical and Biomolecular Engineering, Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

New issue!

Read up on lipids, terminators, NRPSs, and more.

https://pubs.acs.org/toc/asbcd6/12/5

Cover 1: Meng et al report a CRISPR/Cas9 multiplexed integration system in yeast that achieves quadruple integration at an individual locus without pre-engineering.

https://pubs.acs.org/doi/10.1021/acssynbio.2c00591…

2023-05-23

AMB Express

Mining and application of constitutive promoters from Rhodosporidium toruloides.

2023-02-08

PubMed:36754887; DOI:10.1186/s13568-023-01522-1

Xiao Guo¹, Zhenzhen Bai¹, Yang Zhang¹, Huimin Zhao², Shuobo Shi³

Affiliations

Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Engineering, North Third Ring Road 15, Chaoyang District, Beijing, 100029, China
Department of Chemical and Biomolecular Engineering, Carl R. Woese Institute for Genomic Biology, University of IL at Urbana-Champaign, Urbana, IL, 61801, USA.
Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Engineering, North Third Ring Road 15, Chaoyang District, Beijing, 100029, China.

evolutionary-engineering–proteins

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Protein science : a publication of the Protein Society

Directed evolution of angiotensin-converting enzyme 2 peptidase activity profiles for therapeutic applications.

2023-02-16

PubMed:36794431; DOI:10.1002/pro.4597

Pete Heinzelman¹, Philip A Romero¹

Affiliations

Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA

Angewandte Chemie (International ed. in English)

Directed Evolution of an Iron(II)- and α-Ketoglutarate-Dependent Dioxygenase for Site-Selective Azidation of Unactivated Aliphatic C-H Bonds.

2023-02-09

PubMed:36757808; DOI:10.1002/anie.202301370

Christian A Gomez¹, Dibyendu Mondal¹, Qian Du¹, Natalie Chan¹, Jared C Lewis¹

Affiliations

Department of Chemistry, Indiana University, Bloomington, IN 47405, USA

yay, congrats christian for getting this across the finish line! more to come!

2023-03-02

bioRxiv

Laboratory evolution identifies elongated flavodoxins that support electron transfer to sulfite reductases

2023-02-21

DOI:10.1101/2023.02.21.529384

A. Truong, D. Myerscough, I. Campbell, J. T. Atkinson, J. Silberg

Affiliations

Rice University

Laboratory evolution identifies elongated flavodoxins that support electron transfer to sulfite reductases

2023-02-22

human-physiology

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eLife

The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution.

2023-02-21

PubMed:36803543; DOI:10.7554/eLife.83442

Alief Moulana¹, Thomas Dupic¹, Angela M Phillips¹, Jeffrey Chang¹, Anne A Roffler², Allison J Greaney³, Tyler N Starr³, Jesse D Bloom³, Michael M Desai¹

Affiliations

Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States
Biological and Biomedical Sciences, Harvard Medical School, Boston, United States
Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, United States

Multiple mutations may help the Omicron variant escape antibodies. https://elifesciences.org/articles/83442?utm_source=twitter&utm_medium=social&utm_campaign=organic_pr…

2023-02-22

chemical-engineering

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Journal of the American Chemical Society

Waste-Free Fully Electrically Fueled Dissipative Self-Assembly System.

2023-02-06

PubMed:36746118; DOI:10.1021/jacs.2c13140

Dipankar Barpuzary¹, Paul J Hurst², Joseph P Patterson¹, Zhibin Guan¹

Affiliations

Center for Complex and Active Materials, University of California Irvine, Irvine, California92697, United States
Department of Chemistry, University of California Irvine, Irvine, California92697, United States

New paper dropped

2023-02-09

Waste-Free Fully Electrically Fueled Dissipative Self-Assembly System @UCIChemistry @UCIrvine @UFBME #WasteFree #Electrical #Fuel #Dissipative #SelfAssembly

2023-02-07

kedalionlabs.com

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