High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs

Nature biotechnology

Tony P Huang, Zachary J Heins, Shannon M Miller, …, Tina Wang, Ahmad S Khalil, David R Liu

• DOI: 10.1038/s41587-022-01410-2
• PMID: 36076084
• PMCID: PMC9849140