Dysregulation of amino acid metabolism upon rapid depletion of cap-binding protein eIF4E
- Nicholas Ingolia
- May 22, 2023
- kedalionlabs.com
- Paige D Diamond, Nicholas J McGlincy, Nicholas T Ingolia, …, Paige D Diamond, Nicholas J McGlincy, Nicholas T Ingolia
- None, 10.1101/2023.05.11.540079
A parasitic fungus employs mutated eIF4A to survive on rocaglate-synthesizing Aglaia plants
- Nicholas Ingolia
- February 28, 2023
- kedalionlabs.com
- Mingming Chen, Naoyoshi Kumakura, Hironori Saito, …, Takuhiro Ito, Yuichi Shichino, Shintaro Iwasaki
- Elife, 10.7554/elife.81302
Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability
- Nicholas Ingolia
- May 31, 2022
- kedalionlabs.com
- Zhipeng Li, Lucas Ferguson, Kirandeep K Deol, …, Scott J Dixon, Nicholas T Ingolia, James A Olzmann
- Nat Chem Biol, 10.1038/s41589-022-01033-3
Plasmid and Sequencing Library Preparation for CRISPRi Barcoded Expression Reporter Sequencing (CiBER-seq) in Saccharomyces cerevisiae
- Nicholas Ingolia
- May 9, 2022
- kedalionlabs.com
- Ryan Y Muller, Zuriah A Meacham, Nicholas T Ingolia, …, Ryan Y Muller, Zuriah A Meacham, Nicholas T Ingolia
- None, 10.21769/bioprotoc.4376
Analyzing the Composition and Organization of Ribonucleoprotein Complexes by APEX-Seq
- Nicholas Ingolia
- February 16, 2022
- kedalionlabs.com
- Alejandro Padrón, Nicholas Ingolia
- Methods Mol Biol, 10.1007/978-1-0716-1975-9_17
Double stranded DNA breaks and genome editing trigger loss of ribosomal protein RPS27A
- Nicholas Ingolia
- December 16, 2021
- kedalionlabs.com
- Celeste Riepe, Elena Zelin, Phillip A Frankino, …, Samantha G Fernandez, Nicholas T Ingolia, Jacob E Corn
- FEBS J, 10.1111/febs.16321
Dysregulated mRNA Translation in the G2019S LRRK2 and LRRK2 Knock-Out Mouse Brains
- Nicholas Ingolia
- November 11, 2021
- kedalionlabs.com
- Jungwoo Wren Kim, Xiling Yin, Ian Martin, …, Nicholas T Ingolia, Ted M Dawson, Valina L Dawson
- eNeuro, 10.1523/eneuro.0310-21.2021
Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase
- Nicholas Ingolia
- October 15, 2021
- kedalionlabs.com
- Heather E Upton, Lucas Ferguson, Morayma M Temoche-Diaz, …, Nicholas T Ingolia, Randy Schekman, Kathleen Collins
- Proc Natl Acad Sci U S A, 10.1073/pnas.2107900118
The N-terminal domain of SARS-CoV-2Â nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression
- Nicholas Ingolia
- October 8, 2021
- kedalionlabs.com
- Aaron S Mendez, Michael Ly, Angélica M González-Sánchez, …, Nicholas T Ingolia, Jamie H Cate, Britt A Glaunsinger
- Cell Rep, 10.1016/j.celrep.2021.109841
eIF4A inhibitors PatA and RocA stack the deck against translation
- Nicholas Ingolia
- July 2, 2021
- kedalionlabs.com
- Nicholas T Ingolia
- Structure, 10.1016/j.str.2021.06.009
Phosphorylation of mRNA-Binding Proteins Puf1 and Puf2 by TORC2-Activated Protein Kinase Ypk1 Alleviates Their Repressive Effects
- Jeremy Thorner
- Nicholas Ingolia
- July 2, 2021
- kedalionlabs.com
- Henri A Galez, Françoise M Roelants, Sarah M Palm, Kendra K Reynaud, Nicholas T Ingolia, Jeremy Thorner
- None, 10.3390/membranes11070500
Dynamic post-transcriptional regulation by Mrn1 links cell wall homeostasis to mitochondrial structure and function
- Nicholas Ingolia
- April 15, 2021
- kedalionlabs.com
- Kendra Reynaud, Molly Brothers, Michael Ly, Nicholas T Ingolia
- PLoS Genet, 10.1371/journal.pgen.1009521
A genome-scale CRISPR interference guide library enables comprehensive phenotypic profiling in yeast
- Nicholas Ingolia
- March 24, 2021
- kedalionlabs.com
- Nicholas J McGlincy, Zuriah A Meacham, Kendra K Reynaud, Ryan Muller, Rachel Baum, Nicholas T Ingolia
- BMC Genomics, 10.1186/s12864-021-07518-0