Basis for the discrimination of supercoil handedness during DNA cleavage by human and bacterial type II topoisomerases
- Jeffrey Y Jian, Kevin D McCarty, Jo Ann W Byl, …, F Peter Guengerich, Keir C Neuman, Neil Osheroff
- Nucleic Acids Res, 10.1093/nar/gkad190
Zooming into the COVID Era Together
- Emily C Bird, Cathleen C Pettepher, Madeleine A Z Ball, …, Sarah C Reed, Ryan Splittgerber, Neil Osheroff
- None, 10.1007/s40670-022-01611-z
Recognition of DNA Supercoil Handedness during Catenation Catalyzed by Type II Topoisomerases
- Esha D Dalvie, Jordan C Stacy, Keir C Neuman, Neil Osheroff
- Biochemistry, 10.1021/acs.biochem.2c00370
Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms
- Sabrina X Van Ravenstein, Kavi P Mehta, Tamar Kavlashvili, …, Neil Osheroff, David Cortez, James M Dewar
- EMBO J, 10.15252/embj.2022110632
Synthesis and Cytotoxic Evaluation of Arimetamycin A and Its Daunorubicin and Doxorubicin Hybrids
- Eric D Huseman, Jo Ann W Byl, Scott M Chapp, Nathan D Schley, Neil Osheroff, Steven D Townsend
- None, 10.1021/acscentsci.1c00040
Getting stressed over topoisomerase I poisons
- Neil Osheroff
- Cell Chem Biol, 10.1016/j.chembiol.2021.04.015
Topoisomerase II Poisons: Converting Essential Enzymes into Molecular Scissors
- Kendra R Vann, Alexandria A Oviatt, Neil Osheroff
- Biochemistry, 10.1021/acs.biochem.1c00240
