Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Stavroula Kanoni, Sarah E Graham, Yuxuan Wang, …, Cristen J Willer, Themistocles L Assimes, Gina M Peloso
- Genome Biol, 10.1186/s13059-022-02837-1
Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment
- Yota Tatara, Hiromi Yamazaki, Fumiki Katsuoka, …, Shigeyuki Nakaji, Masayuki Yamamoto, Ken Itoh
- Curr Res Transl Med, 10.1016/j.retram.2022.103367
Changes in glial cells and neurotrophic factors due to rotenone-induced oxidative stress in Nrf2 knockout mice
- Maki Inoue-Yanagimachi, Noriko Himori, Keiko Uchida, …, Kazuhiko Namekata, Takayuki Harada, Toru Nakazawa
- Exp Eye Res, 10.1016/j.exer.2022.109314
Establishment of Neh2-Cre:tdTomato reporter mouse for monitoring the exposure history to electrophilic stress
- Hiroshi Kitamura, Tetsuya Oishi, Shohei Murakami, …, Masayuki Yamamoto, Yukio Katori, Hozumi Motohashi
- Free Radic Biol Med, 10.1016/j.freeradbiomed.2022.11.004
Nrf2 deficiency deteriorates diabetic kidney disease in Akita model mice
- Yexin Liu, Akira Uruno, Ritsumi Saito, …, Daisuke Saigusa, Hong Liu, Masayuki Yamamoto
- Redox Biol, 10.1016/j.redox.2022.102525
The KEAP1-NRF2 System and Esophageal Cancer
- Wataru Hirose, Hiroyuki Oshikiri, Keiko Taguchi, Masayuki Yamamoto
- None, 10.3390/cancers14194702
Pathological variants in genes associated with disorders of sex development and central causes of hypogonadism in a whole-genome reference panel of 8380 Japanese individuals
- Naomi Shiga, Yumi Yamaguchi-Kabata, Saori Igeta, …, Masayuki Yamamoto, Nobuo Yaegashi, Junichi Sugawara
- None, 10.1038/s41439-022-00213-w
Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population
- Akiko Hanyuda, Atsushi Goto, Masahiro Nakatochi, …, Makoto Sasaki, Shoichiro Tsugane, Motoki Iwasaki
- Am J Ophthalmol, 10.1016/j.ajo.2022.09.004
Returning individual genomic results to population-based cohort study participants with BRCA1/2 pathogenic variants
- Yohei Hamanaka, Hiroshi Kawame, Nobuo Fuse, …, Yoko Aoki, Takanori Ishida, Masayuki Yamamoto
- Breast Cancer, 10.1007/s12282-022-01404-7
Construction of a trio-based structural variation panel utilizing activated T lymphocytes and long-read sequencing technology
- Akihito Otsuki, Yasunobu Okamura, Noriko Ishida, …, Kengo Kinoshita, Fumiki Katsuoka, Masayuki Yamamoto
- Commun Biol, 10.1038/s42003-022-03953-1
Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium
- Wataru Hirose, Makoto Horiuchi, Donghan Li, …, Fumiki Katsuoka, Keiko Taguchi, Masayuki Yamamoto
- Cell Mol Gastroenterol Hepatol, 10.1016/j.jcmgh.2022.09.004
Protective role of Nrf2 in zinc oxide nanoparticles-induced lung inflammation in female mice and sexual dimorphism in susceptibility
- Radwa Sehsah, Wenting Wu, Sahoko Ichihara, …, Soheir El-Bestar, Emily Kamel, Gaku Ichihara
- Toxicol Lett, 10.1016/j.toxlet.2022.09.004
Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects
- Shaili D Patel, Deepti Anand, Hozumi Motohashi, …, Fumiki Katsuoka, Masayuki Yamamoto, Salil A Lachke
- None, 10.3389/fcell.2022.981893
Blood Lipids and the Risk of Colorectal Cancer: Mendelian Randomization Analyses in the Japanese Consortium of Genetic Epidemiology Studies
- Masao Iwagami, Atsushi Goto, Ryoko Katagiri, …, Shoichiro Tsugane, Kenji Wakai, Motoki Iwasaki
- Cancer Prev Res (Phila), 10.1158/1940-6207.capr-22-0146
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
- Shweta Ramdas, Jonathan Judd, Sarah E Graham, …, Cristen J Willer, Xiang Zhu, Christopher D Brown
- Am J Hum Genet, 10.1016/j.ajhg.2022.06.012
Nrf2 protects against radiation-induced oral mucositis via antioxidation and keratin layer thickening
- Shun Wakamori, Keiko Taguchi, Yuki Nakayama, …, Takenori Ogawa, Yukio Katori, Masayuki Yamamoto
- Free Radic Biol Med, 10.1016/j.freeradbiomed.2022.06.239