Arrestin-dependent nuclear export of phosphodiesterase 4D promotes GPCR-induced nuclear cAMP signaling required for learning and memory
- Joseph M Martinez, Ao Shen, Bing Xu, …, Josephine de Chabot, Jin Zhang, Yang K Xiang
- Sci Signal, 10.1126/scisignal.ade3380
GPCR Signaling Measurement and Drug Profiling with an Automated Live-Cell Microscopy System
- Eric Greenwald, Clara Posner, Ananya Bharath, …, Shu Z Wiley, Paul A Insel, Jin Zhang
- ACS Sens, 10.1021/acssensors.2c01341
Fourier Optical Spin Splitting Microscopy
- Junxiao Zhou, Qianyi Wu, Junxiang Zhao, …, Guanghao Chen, Jin Zhang, Zhaowei Liu
- Phys Rev Lett, 10.1103/physrevlett.129.020801
Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter
- Danielle L Schmitt, Stephanie D Curtis, Anne C Lyons, …, Sohum Mehta, Reuben J Shaw, Jin Zhang
- Nat Commun, 10.1038/s41467-022-31190-x
Rheb regulates nuclear mTORC1 activity independent of farnesylation
- Yanghao Zhong, Xin Zhou, Kun-Liang Guan, …, Xin Zhou, Kun-Liang Guan, Jin Zhang
- Cell Chem Biol, 10.1016/j.chembiol.2022.02.006
Measuring Spatiotemporal cAMP Dynamics Within an Endogenous Signaling Compartment Using FluoSTEP-ICUE
- Julia C Hardy, Sohum Mehta, Jin Zhang, Julia C Hardy, Sohum Mehta, Jin Zhang
- Methods Mol Biol, 10.1007/978-1-0716-2245-2_22
Protocol for reading and imaging live-cell PKA activity using ExRai-AKAR2
- Jin-Fan Zhang, Sohum Mehta, Jin Zhang, Jin-Fan Zhang, Sohum Mehta, Jin Zhang
- STAR Protoc, 10.1016/j.xpro.2021.101071
A Highly Sensitive Fluorescent Akt Biosensor Reveals Lysosome-Selective Regulation of Lipid Second Messengers and Kinase Activity
- Mingyuan Chen, Tengqian Sun, Yanghao Zhong, Xin Zhou, Jin Zhang
- None, 10.1021/acscentsci.1c00919
Liquid-liquid phase separation: Orchestrating cell signaling through time and space
- Qi Su, Sohum Mehta, Jin Zhang
- Mol Cell, 10.1016/j.molcel.2021.09.010
Protocol for using fluorescent sensors targeted to endogenous proteins (FluoSTEPs) to measure microdomain-specific signaling events
- Jason Z Zhang, Brian Tenner, Sohum Mehta, Jin Zhang
- STAR Protoc, 10.1016/j.xpro.2021.100693
Organic Hyperbolic Material Assisted Illumination Nanoscopy
- Yeon Ui Lee, Clara Posner, Zhaoyu Nie, …, Sui Yang, Xiang Zhang, Zhaowei Liu
- Adv Sci (Weinh), 10.1002/advs.202102230