Academic lineage
- Frances H Arnold - Ph.D. student
Gallic Acid: A Natural Phenolic Compound Exerting Antitumoral Activities in Colorectal Cancer via Interaction with G-Quadruplexes
- Victoria Sanchez-Martin, MarÃa Del Carmen Plaza-Calonge, Ana Soriano-Lerma, …, Juan Carlos RodrÃguez-Manzaneque, Miguel Soriano, Jose Antonio Garcia-Salcedo
- None, 10.3390/cancers14112648
Understanding binding affinity and specificity of modular protein domains: A focus in ligand design for the polyproline-binding families
- Jose C Martinez, Francisco Castillo, Javier Ruiz-Sanz, Javier Murciano-Calles, Ana Camara-Artigas, Irene Luque
- Adv Protein Chem Struct Biol, 10.1016/bs.apcsb.2021.12.002
Phage display identification of nanomolar ligands for human NEDD4-WW3: Energetic and dynamic implications for the development of broad-spectrum antivirals
- Francisco Castillo, Carles Corbi-Verge, Javier Murciano-Calles, …, Ronald N Harty, Jose C Martinez, Irene Luque
- Int J Biol Macromol, 10.1016/j.ijbiomac.2022.03.010
A Thermodynamic Analysis of the Binding Specificity between Four Human PDZ Domains and Eight Host, Viral and Designed Ligands
- Eva S Cobos, Ignacio E Sánchez, LucÃa B Chemes, Jose C Martinez, Javier Murciano-Calles
- Biomolecules, 10.3390/biom11081071
The Conformational Plasticity Vista of PDZ Domains
- Javier Murciano-Calles
- None, 10.3390/life10080123
Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95
- Ana Camara-Artigas, Javier Murciano-Calles, Jose C MartÃnez
- Acta Crystallogr D Struct Biol, 10.1107/s2059798319001980
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
- David K Romney, Javier Murciano-Calles, Jöri E Wehrmüller, Frances H Arnold
- J Am Chem Soc, 10.1021/jacs.7b05007
Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity
- Andrew R Buller, Paul van Roye, Javier Murciano-Calles, Frances H Arnold
- Biochemistry, 10.1021/acs.biochem.6b01127
A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation
- Javier Murciano-Calles, David K Romney, Sabine Brinkmann-Chen, Andrew R Buller, Frances H Arnold
- Angew Chem Int Ed Engl, 10.1002/anie.201606242
Common features in the unfolding and misfolding of PDZ domains and beyond: the modulatory effect of domain swapping and extra-elements
- Javier Murciano-Calles, Jofre Güell-Bosch, Sandra Villegas, Jose C Martinez
- Sci Rep, 10.1038/srep19242