rDNA array length is a major determinant of replicative lifespan in budding yeast
- Manuel Hotz, Nathaniel H Thayer, David G Hendrickson, Elizabeth L Schinski, Jun Xu, Daniel E Gottschling
- Proc Natl Acad Sci U S A, 10.1073/pnas.2119593119
Rsp5 and Mdm30 reshape the mitochondrial network in response to age-induced vacuole stress
- Jenna M Goodrum, Austin R Lever, Troy K Coody, Daniel E Gottschling, Adam L Hughes
- Mol Biol Cell, 10.1091/mbc.e19-02-0094
The Upsides and Downsides of Organelle Interconnectivity
- Daniel E Gottschling, Thomas Nyström
- Cell, 10.1016/j.cell.2017.02.030
Selective sorting and destruction of mitochondrial membrane proteins in aged yeast
- Adam L Hughes, Casey E Hughes, Kiersten A Henderson, Nina Yazvenko, Daniel E Gottschling
- Elife, 10.7554/elife.13943
Identification of long-lived proteins retained in cells undergoing repeated asymmetric divisions
- Nathaniel H Thayer, Christina K Leverich, Matthew P Fitzgibbon, …, Philip R Gafken, Jessica J Hsu, Daniel E Gottschling
- Proc Natl Acad Sci U S A, 10.1073/pnas.1416079111
Mother-daughter asymmetry of pH underlies aging and rejuvenation in yeast
- Kiersten A Henderson, Adam L Hughes, Daniel E Gottschling
- Elife, 10.7554/elife.03504
The good and the bad of being connected: the integrons of aging
- Andrew Dillin, Daniel E Gottschling, Thomas Nyström
- Curr Opin Cell Biol, 10.1016/j.ceb.2013.12.003
An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast
- Adam L Hughes, Daniel E Gottschling
- Nature, 10.1038/nature11654
Molecular biology. Fragile delivery to the genome
- Daniel E Gottschling
- Science, 10.1126/science.1225852
Synthetic chromosome arms function in yeast and generate phenotypic diversity by design
- Jessica S Dymond, Sarah M Richardson, Candice E Coombes, …, Srinivasan Chandrasegaran, Joel S Bader, Jef D Boeke
- Nature, 10.1038/nature10403
Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae
- Derek L Lindstrom, Christina K Leverich, Kiersten A Henderson, Daniel E Gottschling
- PLoS Genet, 10.1371/journal.pgen.1002015
Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates
- Joel C Rosenbaum, Eric K Fredrickson, Michelle L Oeser, …, Thomas I Milac, Daniel E Gottschling, Richard G Gardner
- Mol Cell, 10.1016/j.molcel.2010.12.004
Recombination-induced tag exchange to track old and new proteins
- Kitty F Verzijlbergen, Victoria Menendez-Benito, Tibor van Welsem, …, Jacques Neefjes, Daniel E Gottschling, Fred van Leeuwen
- Proc Natl Acad Sci U S A, 10.1073/pnas.0911164107
The mother enrichment program: a genetic system for facile replicative life span analysis in Saccharomyces cerevisiae
- Derek L Lindstrom, Daniel E Gottschling
- Genetics, 10.1534/genetics.109.106229
Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains
- Lazar N Dimitrov, Rachel B Brem, Leonid Kruglyak, Daniel E Gottschling
- Genetics, 10.1534/genetics.109.104497
Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect
- Joshua R Veatch, Michael A McMurray, Zara W Nelson, Daniel E Gottschling
- Cell, 10.1016/j.cell.2009.04.014